ABSTRACT
External beam radiotherapy (EBRT) is one of the important treatment of thyroid cancer. EBRT is still controversial in some aspects of differentiated thyroid cancer. With the development of radiotherapy technology, improvement of equipment and accuracy, treatment complications caused by EBRT are significantly reduced. As a result, EBRT is valued again in the treatment of thyroid cancer, and its indications have been broadened. How to improve the curative effect and guarantee the quality of life becomes the focus of attention. EBRT may be an effective treatment for specific stage and pathological type of thyroid cancer. The multidisciplinary approach is expected to benefit more patients in the future.
ABSTRACT
External beam radiotherapy (EBRT)is one of the important treatment of thyroid cancer. EBRT is still controversial in some aspects of differentiated thyroid cancer. With the development of radiothera-py technology,improvement of equipment and accuracy,treatment complications caused by EBRT are signifi-cantly reduced. As a result,EBRT is valued again in the treatment of thyroid cancer,and its indications have been broadened. How to improve the curative effect and guarantee the quality of life becomes the focus of atten-tion. EBRT may be an effective treatment for specific stage and pathological type of thyroid cancer. The multi-disciplinary approach is expected to benefit more patients in the future.
ABSTRACT
Objective@#To study the clinical results of Coflex and lumbar posterior decompression and fusion in the treatment of lumbar degenerative spondylolisthesis at L4-5.@*Methods@#Thirty-eight patients with Grade Ⅰ degenerative spondylolisthesis, from January 2008 to December 2011 in Beijing Chaoyang Hospital, Capital Medical University were reviewed, and patients were divided into two groups by randomness. Group A was treated with Coflex and group B with pedicle instrumentation and interbody fusion. Fifteen patients were included in group A, and 23 patients were included in group B. In group A, the average age was (56.3±9.1) years. In group B, the average age was (58.2±11.2) years. The clinical results were evaluated by visual analogue scale (VAS) and Oswestry disability index (ODI). Slip distance (SD) was measured before and after surgery, and the changes of intervertebral angle at index level and adjacent level were also recorded.@*Results@#The follow-up period was 36 to 68 months, with the average of (39±14) months in the both groups. The operation time and bleeding volume of patients in group A were significantly less than that of group B (P<0.05). In both groups, the difference of ODI and VAS before operation and postoperative follow-up were statistically significant (P<0.05). There was no significant difference between lumbar intervertebral angle and the sliding distance in group A at all time points. In the group B, there was a significant increase in the intervertebral angle and the sliding distance at L3-4 and L5-S1 level after surgery, the difference at upper and below adjacent segment before and after surgery were statistically significant.@*Conclusions@#Coflex interspinous dynamic stabilization system has same excellent clinical results as pedicle screw instrumentation and fusion surgery for the treatment of L4-5 degenerative spondylolisthesis; no significant progression of spondylolisthesis been observed during more than 3 years follow-up, and no obvious adjacent segment degeneration has been found.
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Objective To investigate the clinical value of digital subtraction angiography (DSA) interventional thrombolysis in the treatment of acute cerebral infarction.Methods 35 patients with acute cerebral infarction were divided into 6h group and 7-12h group in accordance with DSA from the onset time.Before and after thrombolytic therapy,the nerve function defect angiographic recanalization rate and postoperative score of therapeutic effect evaluation were compared between the two groups.Results In the 6h group,the recanalization rate ＞ 70％ (33.33 ％) and the recanalization rate ＞50％ (83.33％) were significantly higher than those in the 7-12h group (18.18％,55.55％),and the differences were statistically significant(x2 =6.56,5.02,all P ＜ 0.05).Before treatment,the ESS score between the two groups was not statistically significantly different(t =0.83,P ＞ 0.05).After treatment for 1d,7d,14d,ESS scores of the two groups [(62.44 ± 9.82) points,(68.95 ± 11.23) points,(73.89 ± 11.24) points,(54.67 ± 9.11) points,(58.02 ± 10.47) points,(61.43 ± 10.23) points] were significantly higher than those before treatment [(42.12 ± 8.79) points,(41.92 ± 9.02) points,t =6.87,7.03,7.92,6.03,6.56,6.77,all P ＜ 0.05].After treatment for 1 d,7d,14d,the ESS scores of the 6h group [(62.44 ± 9.82) points,(68.95 ± 11.23) points,(73.89 ± 11.24) points] were significantly higher than those of the 7-12h group [(54.67 ± 9.11) points,(58.02 ±10.47) points,(61.43 ± 10.23) points],and the differences were statistically significant(t =5.45,5.10,4.23,all P ＜ 0.05).Conclusion DSA interventional thrombolytic therapy can significantly improve the neurological status of the patients,and the onset time is shorter.The clinical treatment is better.In the clinical treatment,we should grasp the opportunity.
ABSTRACT
To observe the changes of intelligence in cerebral infarction patients, and to explore the relationship between intelligence and brain CT feature. Methods:The intelligence was measured by WAIS-RC in 80 cerebral infarction patients.Results:The VIQ and FIQ reduced significantly in the patients with hypertension. FIQ in patients with diabetes mellitus and PIQ in patients with cerebral vesscular disease histories reduced significantly. The PIQ reduced significantly in the patients of right focus on CT. VIQ, PIQ and FIQ reduced significantly in patients of cerebral cortices involved. But the number of focus, thalamus involved and cerebral atrophy were of no significance.Conclusion:The intelligence of the cerebral infarction patients companying hypertension, diabetes mellitus and several cerebral vesscular disease histories was impaired significantly. Cerebral cortices involed was the most important factor among the features on CT relating to intelligence quotient.
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Eight adult dogs distributed equally into control and therapy groups were fed on stock diet for 20 days and then irradiated whole-bodily with 60Co 4.65 Gy. After irradiation the control group was not given any therapeutic measure but fed on the diet as usual, while the therapy group was given with a larger amount of vitamins and high-caloric and high-protein diet, and sometimes force feeding was taken if the latter showed sign of anorexia. Whether higher values of nonprotein nitrogen in serum of two dogs in restored period and diarrhea happened in the therapy group were attribute to The treatments such as high-protein diet and force feeding were still unknown, the curing effects of nutrition and antibiotics were distinct as shown in that the body weight was easily maintained, and that the anemia and leucopenia wereless severe and recovered early. Moreover, within 30 days both the ther apy andcontrol groups one dog died respectively but survival time of the former was longer than the latter.
ABSTRACT
Water and salt requirements were studied in 17 and 18 healthy young men respectively. Each subject walked in a hot and humid environment (DB 28-34℃, RH 50-76%) at a speed of 5 km/hr with backpack loads of 15-25 kg for four hours. Dehydration would occur if no water or inadequate water was supplied and it would affect circulatory, sweating and thermore-gulatory function. It was suggested that MCHC= mightbeasensitive index to determine whether the body was dehydrated or not and to evaluate adequate amount of drinking water. The results showed that water loss should be replaced preferably by periodic intake of small amounts of water throughout the work period and the total amount required was about 80% of sweat loss. Thus, the rise of body temperature and heart rate was less than that of the subjects drinking 250 ml/hr of water or drinking voluntarily and there was little change in MCHC. The results also showed that the loss of salt by sweating was closely related to heat acclimatization. Therefore it is imporatnt to provide adequate salt to those unacclima-tized. Those taking 20 gm/day had a mild increase of rectal temperature and heart rate during work period and their urinary excretions of chloride were above 5 gm/day. According to the experiment, 20 gm/day of salt gave a satisfactory result.